ORAL ANTIDIABETICS & RELATED DRUGS
International Brand Name:
In treatment of:
treatment of type Diabetes Mellitus
5.Elevated serum transaminase levels (rare)
1 Hypersensitivity to the drug
5.Partial intestinal obstruction
6.Chronic intestinal diseases
8.Severe renal impairment
9.History of abdominal surgery
1.Mild to moderate renal impairment
2.Monitor hepatic function tests during therapy
3.Enhance hypoglycaemic effects of sulfonylureas. Give glucose in such situations.
Sucrose: Abdominal discomfort or diarrhoea.
Digestive enzymes (amylase, pancreatin) and intestinal adsorbents (charcoal): Reduce efficacy of acarbose.
Sulphonylureas, biguanides: Acarbose increases their efficacy.
Insulin: In IDDM, insulin requirement is reduced.
Oral: Start with 25mg thrice daily with the 1st bite of each main meal. Increased to 50mg thrice daily; at 4 to 8 week intervals based on 1st hour postprandial glucose levels and tolerance. Then increased to 100mg thrice daily if required.
Maintenance dosage: 50mg to 100mg thrice daily; depending up on the patient`s weight.
Maximum dose: 200mg thrice daily.