ANTI COAGULANTS THROMBOLYTICS & ANTIPLATLET DRUGS
International Brand Name:
In treatment of:
Mgt of Thromboembolic disorders
1.Hypersensitivity to the drug
3.Ulceration of gastrointestinal tract
4.In sub acute bacterial endocarditis
6.Increased capillary permeability
7.Within one day of surgery or labour
Use with caution in following conditions:
3.Gastrointestinal tract disorders
5.Immediately after surgery
Drugs which enhance efficacy of Acenocoumarol: NSAIDs, Amiodarone, Antibacterial agents (Cotrimoxazole, Cephalosporins, Erythromycin, Quinolone antibiotics, Chloramphenicol, Doxycycline, INH, Neomycin) Cimetidine, Allopurinol, Diuretics and Oral anticoagulants.
Drugs which decrease efficacy: Bismuth bicarbonate, Rifampicin, Barbiturates, Griseofulvin, Magnesium.
Oral hypoglycemic agents: Efficacy of these enhanced.
Vit. K: Reverses effects
Starts with 8 to12mg on 1st day. 4 to 8mg on 2nd day.
Maintenance dosage: 1 to 8mg daily.