ALFACALCIDOL

Product: 
ALFACALCIDOL
Formulary: 
Generic Formulary
Category: 
Nutrition & Metabolism
Sub Group: 
VITAMINS
International Brand Name: 
One-Alpha
Dosages: 
0.25 MCG/0.50 Mcg
Unit of Packing: 
Capsule
In treatment of: 
Treatment of Hypocalcaemia
Adverse Effects: 
1.Hypercalcaemia 2.Fatigue 3.Weakness 4.Diarrhoea 5.Vomiting 6.Sluggishness 7.Albuminuria 8.Polyuria 9.Calcification of soft tissues (blood vessels, parenchymal organs including heart) 10.Renal stones 11.Growh retardation in children 12.Hypertension 13.Anorexia 14.Nausea 15.Constipation 16.Hyperphosphataemia.
Contraiindication: 
1.Hypercalcaemia 2.Hypervitaminosis D 3.Hyperphosphataemia (except when occurring with hypoparathyroidism 4.Hypermagnesaemia.
Special Precaution: 
1 Renal impairment 2.Hypercalciurea 3.Renal stones 4.Coronary diseases.
Interaction: 
Digitallis preparations: Cardiac arrhythmias precipitated. Thiazide Diuretics: Hypercalcaemic response enhanced. Barbiturates & other enzyme inducing anticonvulsants: Reduce efficacy. Minteral Oil: Prolonged use reduces efficacy. Cholestyramine, Cholestipol, Sucralfate, Aluminium based Antacids: Reduced efficacy by decreasing absorption of alfacalcidol. Magnesium based Antacids or Laxatives: Hypermagnesaemia in those on chronic renal dialysis.
Servings: 
Oral: Starts with 1mcg daily. Adjusted based on patients response to 2mcg daily if required. Children over 20kg: Starts with 1mcg daily. Adjusted based on patient`s response. Children under 20kg: 0.5mcg daily or 0.05mcg/kg/day

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