Generic Formulary
Infections & Infestations
Sub Group: 
International Brand Name: 
100MG; 250 mg; 500 mg
Unit of Packing: 
Inj- 2ml
In treatment of: 
Treatment of severe infection caused by susceptible bacteria
Adverse Effects: 
1.Cochlear damage & hearing loss(ototoxicity) 2.Nephrotoxicity 3.Neuro muscular disorders
1.Hypersensitivity to the drug or other amino glycosides 2.Never use along with other nephrotoxic drugs
Special Precaution: 
1.Renal impairment 2.Neuromuscular disorders 3. Auditory disorders
Amphotericin B, Cisplatin, Cephalosporin, Vancomycin, Methoxyflurane, Frusemide, Bumetanide: Increased nephrotoxicity. Anaesthetics, Neuromuscular blocking agents (Tubocurarine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in Pseudomonas infections. Loop diuretics: Concurrent use of these agents may increase the risk of respiratory paralysis and renal dysfunction. Lab Tests: Aminoglycoside serum levels: Guard against in-vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Adults & Children: 15mg/kg/day in 1 to 3 doses; given intravenously or Intramuscularly Adults: 4 to 20 mg intrathecally as single dose. Tuberculosis: 15mg/kg/day 5 times weekly Urinary Tract Infections: 7.5 mg/kg/day Neonates: 10mg/kg intramuscularly or intravenously followed by 7.5 mg/kg twice Daily.

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