Infections & Infestations
International Brand Name:
In treatment of:
Treatment of severe infection caused by susceptible bacteria
1.Cochlear damage & hearing loss(ototoxicity)
3.Neuro muscular disorders
1.Hypersensitivity to the drug or other amino glycosides
2.Never use along with other nephrotoxic drugs
3. Auditory disorders
Amphotericin B, Cisplatin, Cephalosporin, Vancomycin, Methoxyflurane, Frusemide, Bumetanide: Increased nephrotoxicity.
Anaesthetics, Neuromuscular blocking agents (Tubocurarine): Risk of neuromuscular blockade and respiratory paralysis.
Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in Pseudomonas infections.
Loop diuretics: Concurrent use of these agents may increase the risk of respiratory paralysis and renal dysfunction.
Lab Tests: Aminoglycoside serum levels: Guard against in-vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Adults & Children: 15mg/kg/day in 1 to 3 doses; given intravenously or Intramuscularly
Adults: 4 to 20 mg intrathecally as single dose.
Tuberculosis: 15mg/kg/day 5 times weekly
Urinary Tract Infections: 7.5 mg/kg/day
Neonates: 10mg/kg intramuscularly or intravenously followed by 7.5 mg/kg twice Daily.