AMPHOTERICIN B

Product: 
AMPHOTERICIN B
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIFUNGALS
International Brand Name: 
Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec
Dosages: 
50 MG
Unit of Packing: 
Vial
In treatment of: 
Treatment of Oral or Perioral Candidiasis
Adverse Effects: 
1.Pain at the site of injection 2.Fever 3.Chills 4.Nausea 5.Vomiting 6.Myalgia 7.Hearing loss 8.Thrombocytopenia 9.Anaphylactoid reactions 10.Thrombophlebitis 11.Tinnitus 12.Anorexia 13.Apnoea 14.Hypotension
Contraiindication: 
1.Hypersensitivity to Amphotericin B
Special Precaution: 
1.Renal impairment, 2. Hepatic dysfunction
Interaction: 
Corticosteroids: Hypokalaemia. Digitalis: Enhances digitalis toxicity. Cyclosporine, Aminoglycosides: Increase in nephrotoxic effects. Betoconazole: Antagonism with betoconazole. Flucytosine: Synergy.
Servings: 
Adult: Initial dose: 1 mg IV; Next day 0.25 mg / kg. / Day followed by an increase in dose of 5 - 10 mg every day. Maximum daily dose: 1 mg / kg body weight / day

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