Anastrozole

Product: 
Anastrozole
Formalary: 
Specialty Formalary
Category: 
Oncology
Trade Name: 
Arimidex
Packing: 
Tablet
Potency: 
1mg
In Treatment of: 
Anastrozole is used with other treatments, such as surgery or radiation, to treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods). This medication is also used in women, who have experienced menopause, as a first treatment of breast cancer that has spread within the breast or to other areas of the body. This medication is also used to treat breast cancer in women whose breast cancer has worsened after taking tamoxifen (Nolvadex). Anastrozole is in a class of medications called nonsteroidal aromatase inhibitors. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow
Adverse Effects: 
Anastrozole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: 1. Weakness 2. Headache 3. hot flashes 4. sweating 5. stomach pain 6. nausea 7. vomiting 8. loss of appetite 9. constipation 10. diarrhea 11. heartburn 12. weight gain 13. joint, bone, or muscle pain 14. breast pain 15. mood changes 16. depression 17. difficulty falling asleep or staying asleep 18. nervousness 19. dizziness 20. vaginal bleeding 21. vaginal dryness or irritation 22. pain, burning, or tingling in the hands or feet 23. dry mouth 24. hair thinning Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately: 1. chest pain 2. sore throat, cough, fever, chills, swollen glands, or other signs of infection 3. swelling, redness, or warmth in hand or arm 4. difficult, painful, or urgent urination 5. blurred vision or vision changes 6. yellowing of the skin or eyes 7. pain in the upper right part of the stomach 8. skin lesions, ulcers, or blisters 9. rash 10. hives 11. itching 12. shortness of breath 13. difficulty swallowing or breathing 14. swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs Anastrozole may cause or worsen osteoporosis. It can decrease the density of your bones and increase the chance of broken bones and fractures.
Contraindication: 
Conditions: Disease of Inadequate Blood Flow to the Heart Muscle, Decreased Calcification or Density of Bone, Pregnancy, A Mother who is Producing Milk and Breastfeeding, High Cholesterol Allergies: LETROZOLE ANALOGUES
Special Precaution: 
Before taking anastrozole, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, high blood pressure, heart disease (such as ischemic heart disease, history of chest pain), brittle bone disease (osteoporosis), blood clots.This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages. Anastrozole is used mainly in women after menopause. If you have not gone through menopause and your doctor has prescribed this for you, this medication must not be used during pregnancy. It may cause harm to an unborn baby or miscarriage. If you become pregnant or think you may be pregnant, tell your doctor immediately. Women of childbearing age should use reliable form(s) of contraception (such as latex condoms) during treatment. Products containing estrogen (such as birth control pills) should not be used. Consult your doctor for more details.It is not known whether this drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.
Interaction: 
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. This drug should not be used with the following medications because very serious interactions may occur: estrogens, tamoxifen. If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting anastrozole. Before using this medication, tell your doctor or pharmacist of all prescription and non prescription/herbal products you may use. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Dosages: 
Anastrozole comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take anastrozole at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take anastrozole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. You may need to take anastrozole for several years or longer. Continue to take anastrozole even if you feel well. Do not stop taking anastrozole without talking to your doctor. Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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