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AZATHIOPRINE
Product:
AZATHIOPRINE
Formulary:
Generic Formulary
Category:
Immunosuppressants
Sub Group:
IMMUNOSUPPRESANTS
International Brand Name:
Azason,Imuron,Azamun,Imurel
Dosages:
50 mg
Unit of Packing:
Tablets
In treatment of:
Prevention of rejection in Organ and tissue transplant
Adverse Effects:
1. Nausea
2. Vomiting
3. lowered resistance to infection
4. Bruising or unusual bleeding
5. Anemia
6. Weakness
7. sore in mouth
8. Taste changes
9. Diarrhea
10. Loss of appetite
11. Visual changes
12. Black, tarry stools
13. Blood in urine or in stool
14. Cough or hoarseness
15. Fever
16. Chills
17. Lower back or side pain
18. Painful or difficult urination
19. Pinpoint red spot on skin
20. Slurred speech
21. Swelling on leg or lower leg
22. Shortness of breath
23. Bloody vomiting
24. Thinned or brittle hair
25. Mouth blistering
26. Thrombocytopenia
27. Leucopenia
28. Coma
29. Seizures
30. Pancytopenia
31. Agranulocytosis
32. Aplastic anemia
33. Myalgia
34. Hypocalcaemia
35. Alopecia
Contraiindication:
Contraindicated in patients with hypersensitivity to the drug or its ingredients
Special Precaution:
1. Renal impairment
2. Hepatic dysfunction
Interaction:
Servings:
Oral-
Adult-
To prevent rejection of kidney transplants: 3-5mg/kg/day beginning on 1st day to 3rd days before transplantation. Maintenance dose is 1-3mg/kg/day
Children- Same as adult
Rheumatoid arthritis
Adults-
1mg/kg as a single dose or in divided doses-
