AZITHROMYCIN

Product: 
AZITHROMYCIN
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
ACNE
International Brand Name: 
Zomax ,Azitam ,Zocin ,Azomyne
Dosages: 
100 MG; 250 mg/500 mg/ 100 mg/5ml/200 mg/5 ml
Unit of Packing: 
Tablets- Distab
In treatment of: 
ANTIACNE- MILD OR MODERATE ACNE
Adverse Effects: 
1. Nausea 2.Vomiting 3.Diarrhoea 4.Epigastric pain 5.Angioedema 6.Rash 7.Urticaria 8.Headache 9.Dizziness 10.Fever 11.Cholestatic jaundice 12.Hearing disturbances 13.Vertigo
Contraiindication: 
1.Hypersensitivity to Azithromycin and other macrolide
Special Precaution: 
1.Renal impairment 2.Hepatic dysfunction
Interaction: 
Aluminium & Magnesium containing Antacids: Decrease peak serum levels. Theophylline: Serum concentration of Theophylline increased. Warfarin: Anticoagulant effects enhanced. Digoxin & Cyclosporine: Increase in their serum concentration. Carbamazepine: Toxicity occurs which may require hospitalization. Triazolam: Increases serum levels of Triazolam leading to toxicity. Ergot Alkaloids: Acute ergotism manifested as peripheral ischaemia. Food: Absorption reduced by as much as 52% (should be taken 1 hr before or 2 hrs after meal).
Servings: 
Adult: 500 mg once daily for 1 day followed by 250 mg once daily for 4 days. For the treatment of urethritis and cervicitis: 1 - 2 g as a single dose Prophylaxis of MAC: 1200 mg once weekly Chancroid: 1000 mg as a single dose Children: 10 mg / kg body weight once daily on 1 day followed by 5 mg / kg body weight once daily for 4 days.

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