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AZTREONAM
Product:
AZTREONAM
Formulary:
Generic Formulary
Category:
Infections & Infestations
Sub Group:
ANTIBACTERIALS
International Brand Name:
Azactom
Dosages:
1 GM; 2 gm; 500 mg
Unit of Packing:
Vial
In treatment of:
Bone & joint infections;Gonorrhea,intra-abdominal infections;lower RTI Meningitis;Speticemia;skin and soft tissue infections;UTI,pseudomonal infections in cystic fibrosis(RTIs),pelvic infections, treatment of infections caused by susceptible GM+ve aerobic organisms
Adverse Effects:
1.Nausea
2.Diarrhea
3.Vomiting
4.Headache
5.Seizures
6.Elevation of liver enzymes & creatinine
7.Swelling & discomfort at I.M. injection site & thrombophlebitis at I.V. injection site.
8.Hypersensitivity reactions
9.Neutropenia
10.Pancytopenia
11.Thrombocytopenia
Contraiindication:
1.Hypersensitivity to Aztreonam
Special Precaution:
1.Renal impairment
2.Hepatic impairment
3.Avoid use together with other beta lactum antibiotics & amino glycosides because additive effects occur
4.Avoid use together with Probenecid, Chloramphenicol, Clavulanic acid etc.
Interaction:
None with gentamicin, metronidazole, cephrodine, clindamycin, nafcillin or frusemide.
Servings:
0.5gm to 2gm I.V. or I.M. twice daily or thrice daily
In severe infections: 2gm I.M or I.V.; 3 times daily to 4 times daily
Maximum dose: 8gm/day
Gonorrhea: 1gm intramuscularly as a single dose
