AZTREONAM

Product: 
AZTREONAM
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Azactom
Dosages: 
1 GM; 2 gm; 500 mg
Unit of Packing: 
Vial
In treatment of: 
Bone & joint infections;Gonorrhea,intra-abdominal infections;lower RTI Meningitis;Speticemia;skin and soft tissue infections;UTI,pseudomonal infections in cystic fibrosis(RTIs),pelvic infections, treatment of infections caused by susceptible GM+ve aerobic organisms
Adverse Effects: 
1.Nausea 2.Diarrhea 3.Vomiting 4.Headache 5.Seizures 6.Elevation of liver enzymes & creatinine 7.Swelling & discomfort at I.M. injection site & thrombophlebitis at I.V. injection site. 8.Hypersensitivity reactions 9.Neutropenia 10.Pancytopenia 11.Thrombocytopenia
Contraiindication: 
1.Hypersensitivity to Aztreonam
Special Precaution: 
1.Renal impairment 2.Hepatic impairment 3.Avoid use together with other beta lactum antibiotics & amino glycosides because additive effects occur 4.Avoid use together with Probenecid, Chloramphenicol, Clavulanic acid etc.
Interaction: 
None with gentamicin, metronidazole, cephrodine, clindamycin, nafcillin or frusemide.
Servings: 
0.5gm to 2gm I.V. or I.M. twice daily or thrice daily In severe infections: 2gm I.M or I.V.; 3 times daily to 4 times daily Maximum dose: 8gm/day Gonorrhea: 1gm intramuscularly as a single dose

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