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BISOPROLOL
Product:
BISOPROLOL
Formulary:
Generic Formulary
Category:
Cardio Vascular System
Sub Group:
ANTIANGINALS & CORONORY VASOLIDATORS
International Brand Name:
Concor,Zebeta,Monocor
Dosages:
2.5 MG/5 mg/10 mg
Unit of Packing:
Tablets
In treatment of:
Management of Hyper Tension(HTN) and Angina Pectoris
Adverse Effects:
1.Heart failure
2.Heart block
3.Nightmares
4.Gastrointestinal problems
5.Nausea
6.Tiredness
7.Sinus bradycardia
8.Depression
9.Rash
10.Hypotension
11Dizziness
12.Depression
13.Fatigue
14.Vomiting
15.Diarrhoea
16.Constipation
17.Headache
18.Bronhospasm
19.Sleep disturbances
20.Cold extremities
21.Rhinitis
22.Sinusitis
23.Edema
24.Impotence
25.Coughing
26.Myalgia
27.Arthralgia
Contraiindication:
1.Hypersensitivity to the drug
2.Second or third degree heart block
3.Congestive heart failure
4.Cardiogenic shock
5.Sinus Bradycardia
6.Chronic obstructive pulmonary diseases
7.Bronchial asthma
9.Peripheral arteriolar disorders
10.Renal impairment.
Special Precaution:
1.Left ventricular failure
2.Hepatic impairment
3.The drug should be gradually withdraw with caution
4.Respiratory disorders
5.Diabetes mellitus
6.General Anaesthesia
7.Thyrotoxicosis
8.Use with caution along with class-1 antiarrrythmic drugs & other anti hypertensive drugs.
Interaction:
Alcohol, Anxiolytics and Hypnotics, Cimetidine, Diuretics: Enhanced hypotensive effect.
Analgesics: NSAIDs antagonise hypotensive effect.
Antidiabetics: Enhanced hypoglycaemic effect.
Calcium channel blockers: Increase risk of bradycardia and AV block with diltiazem, severe hypotension and heart failure with verapamil, nifedipine.
Cardiac glycosides: Increased AV Block and brandycardia.
Cholinergics: Effects antagonised by bisoprolol.
Corticosteroids: Antagonism of hypotensive effect.
Sympathomimetics: Severe hypertension with adrenaline and noradrenaline.
Servings:
2.5mg to 10mg 0nce daily depending upon the patient`s response
Maximum dose: 20mg/day
