BLEOMYCIN

Product: 
BLEOMYCIN
Formulary: 
Generic Formulary
Category: 
Neoplastics
Sub Group: 
ANTI NEOPLASTIC AGENTS
International Brand Name: 
Blenoxane.
Dosages: 
15 Mg/IU
Unit of Packing: 
Vial
In treatment of: 
TREATMENT OF SQUAMOUS CELL OR TESTICULAR TUMOURS; TREATMENT OF LYMPHOMA
Adverse Effects: 
1. Nausea 2. Vomiting 3. Painful or difficult urination 4. Bruising or unusual bleeding 5. Anemia 6. Weakness 7. sore in mouth 8. Taste changes 9. Diarrhea 10. Loss of appetite 11. Visual changes 12. Black, tarry stools 13. Blood in urine or in stool 14. Cough or hoarseness 15. Fever 16. Chills 17. Lower back or side pain 18. Lymphoma 19. Pinpoint red spot on skin 20. Slurred speech 21. Swelling on leg or lower leg 22. Shortness of breath 23. Pulmonary fibrosis 24. Hepatotoxicity 25. Alopecia 26. Pneumonites 27. Hypotension 28. Wheezing 29. Raynaud`s phenomenon
Contraiindication: 
1. Hypersensitivity to the drug 2. Pulmonary diseases
Special Precaution: 
1. Hypersensitivity to drug 2. Anesthesia 3. Lowered resistance to infection 4. Monitor patient pulmonary function closely
Interaction: 
Digoxin: Decreased serum levels of digoxin. Phenytoin: Decrease serum levels of phenytoin. Radiotherapy: Enhanced toxicity. O2 Therapy: Enhanced pulmonary toxicity. Cisplatin: Toxicity increased by bleomycin. Vincristine: Debilitation syndrome.
Servings: 
Adults- 0.25 to0.5unit/kg or 10 to 20units/metre square vials given once or twice a week through subcutaneous, intramuscular and intravenous administration.1 unit/day or 5 unit/week is given as maintenance dose.

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