BROMOCRIPTINE

Product: 
BROMOCRIPTINE
Formulary: 
Generic Formulary
Category: 
Endocrine System
Sub Group: 
GONADOL HORMONE & RELATED DRUGS
International Brand Name: 
Parlodel
Dosages: 
1.25 MG/2.5 mg
Unit of Packing: 
Tablets
In treatment of: 
Hypogonadism;Galactorrhea;Infertility
Adverse Effects: 
1.Hypotension 2.Nausea 3.Vomiting 4.Constipation 5.Headache 6.Dizziness 7.Skin rash 8.Dry mouth
Contraiindication: 
1.Hypersensitivity to Bromocriptine and other ergot derivatives 2.Preeclampsia
Special Precaution: 
1.Renal impairment 2.Hepatic impairment 3.Myocardial infarction 4.Arrhythmia 5.History of psychosis 6.Peptic ulcer 7.Diabetes mellitus 8.Concurrent antihypertensive therapy. 9.Use caution when driving vehicle operating machine or activities requiring mental alertness
Interaction: 
Antihypertensives: Efficacy potentiated by concomitant use of bromocriptine dopamine antagonists. Phenothiazines, butyrophenones: Decreases efficacy of these drugs. Erythromycin: increases efficacy of bromocriptine. Alcohol: Decreases tolerance to bromocriptine and vice-versa.
Servings: 
Adult: Parkinson`s disease: Initial dose: 1 - 1.25 mg at night with food for 1 week. 2 - 2.5 mg at night with food for 2nd week 5 mg / day in 2 divided doses for 3rd week 7.5 mg / day in 3 divided doses for 4th week.Then increase the dose by 2.5 mg daily every 3 - 14 days until sufficient therapeutic response is obtained Maintenance dose: 10 - 40 mg/day.Maximum dose: 100 mg / day Amenorrhea and Galactorrhea associated with hyperprolactinemia: Initial dose: 1.25 - 2.5 mg / day increase the dose by 2.5 mg daily every 3 - 7 days until sufficient therapeutic response is obtained. Maintenance dose: 5 - 7.5 mg/day.Maximum dose: 40 mg / day Acromegaly: Initial dose: 1.25 - 2.5 mg at night for 3 days increase the dose by 1.25 - 2.5 mg daily every 3 - 7 days until sufficient therapeutic response is obtained.Dose range: 20 - 30 mg / day in divided doses. Maximum dose: 100 mg / day Hepatic encephalopathy: Initial dose: 1.25 mg / day increase the dose by 1.25 mg every 3 days until sufficient therapeutic response (15 mg) is obtained. Premenstrual syndrome 5 -15 mg in 2 divided doses 10th day of menstrual cycle until onset of menstruation Cushing`s syndrome: 1.25 - 2.5 mg 2 - 4 times daily Suppression of established lactation: 2.5mg daily for 2 to 3 days. Subsequently increased to 2.5mg twice daily for two weeks. Children: Not recommended

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