International Brand Name:
In treatment of:
Termination of pregnency 2nd Trimester,treatment of postpartum haemorrhage
5. Cardiac arrest.
7. Redness around injection site.
9. Facial flushing.
10. Increase in body temperature.
12. Pulmonary oedema
1. Hypersensitivity to the drug.
2. Cardiovascular diseases.
3. Kidney disease.
4. Liver disease.
5. Lung disease.
6. Recent infection of the ovaries, fallopian tubes and uterus
6. High blood pressure.
9. Scarring of the womb.
Oxytocin: Activity of oxytocin augmented and hence should be used sequentially and carefully monitored.
Hyperosmolar Urea: Prior injection of urea enhances activity of carboprost.
Mifepristone: Enhanced activity with fewer side effects.
Termination of pregnancy:
250 mcg at intervals of 1.5-3.5 hours, depending on uterine response; may increase dose to 500 mcg if contractility is inadequate after several 250 mcg doses. Dose should not exceed 2 mg
Control of hemorrhage:
250 mcg; additional doses may be administered between 15 and 90 minutes apart if needed. Dose should not exceed 2 mg
400-500mcg diluted in 50mL NS and instilled into the bladder; clamp catheter and allow solution to dwell for 60 minutes; repeat every 6 hours until response. Patient should change positions every 15 minutes while carboprost is in bladder