Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
3.125 MG/6.25 mg/12.5 mg/25 mg
Unit of Packing: 
In treatment of: 
Management of Hyper Tension(HTN)
Adverse Effects: 
1.Gastrointestinal disturbances;2.Dry eyes;3.Dizziness4.Syncope5.Depression6.Dyspnoea7.Drowsiness8.Headache9.Postural hypotension10.Bradycardia
1.Uncontrolled heart failure2.Second or third degree heart block3.Cardiogenic shock4.Bradycardia5.Bronchospasm6.Hypersensitivity to the drug7.Chronic obstructive pulmonary diseases8.Hypoglycemia9.Haemorrhage10.Hepatic impairment
Special Precaution: 
1.Cardiac failure2.Peripheral vascular diseases3.Chronic obstructive pulmonary diseases4.Diabetes mellitus5.Hyperthyroidism6.Postural hypotension7.Avoid driving or any other activities requiring consciousness8.The drug should be gradually withdraw with caution
Antidiabetic agents : Effects of insulin and oral hypoglycaemics enhanced.Calcium blockers : Isolated cases of conduction disturbance have been observed.Clonidine: Blood pressure and heart rate lowering effects potentiated.Digoxin : Serum concentrations of digoxin are increased requiring monitoring of digoxin.Rifampicin : Plasma concentration of carvedilol reduced by 70%.
Initial dosage: 6.25mg to 12.5mg once daily for 2days. Increases the dosage by 12.5mg up to 50mg once daily based on patient`s response.Congestive heart failure: Starts with 3.125mg and gradually increases to 25mg 12th hourly. Angina: Starts with 12.5mg 12th hourly and gradually increases to 25-50mg 12th hourly

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