Generic Formulary
Infections & Infestations
Sub Group: 
International Brand Name: 
Cefachlor,Cefaclorum,Ceclor,Distaclor, keflor,Roniclor
375 MG; 250mg;125 mg; 187 mg/5 ml
Unit of Packing: 
In treatment of: 
Treatment of UTIS;upper and lower RTIS;skin infections;Otitis media
Adverse Effects: 
1.Nausea 2.Vomiting 3.Diarrhea 4.Gastritis 5.Super infection 6.Candidiasis 7.Rash 8.Hypersensitivity reactions 9.Joint pain 10.Vaginitis 11.Neutropenia 12.Thrombocytopenia 13.Headache 14.Dizziness 15.Hallucinations 16.Nephritis 17.Elevated liver enzymes.
1.Hypersensitivity to cephalosporins 2.Neuromuscular disorders
Special Precaution: 
1.Renal impairment 2.Neuromuscular disorders 3.Those allergic to penicillins
Aminoglycosides (Gentamycin, Tobramycin): Nephrotoxicity of aminoglycosides potentiated. Bacteriostatic agents like Chloramphenicol: Decrease efficacy of Cefaclor. Probenecid: Slows tubular excretion and this enhances efficacy. Frusemide & Ethacrynic Acid: Potentiate nephrotoxicity of Cefaclor. Lab.test: Urine Glucose: False positive with Benedicts solution and Fehlings solution. Direct Coomb
Adults: 0.25gm to 0.5gm orally three times daily or four times daily Urinary tract infections: 2gm once daily orally Children: 20mg/kg/day to 40mg/kg/day based on severity of infections

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