Generic Formulary
Infections & Infestations
Sub Group: 
International Brand Name: 
Cefazoline,Cephazolin, Anuf,Cefacidal, Cefamezin,Cefina, Elzogram,Faxilen, Gomaxin, Kefazol,Kefol,Kefzol, Kefzolon
1GM INJ; 250 mg;500mg
Unit of Packing: 
In treatment of: 
Treatment of Billiary tract infections,Staphylococcal Endocarditis and peritonitis
Adverse Effects: 
1.Pain after I.M. injection & thrombophlebitis after I.V. injection 2.Rashes 3.Allergic manifestation 4.Vaginitis 5.Pruritis 6.Candidiasis 4.Nephrotoxicity 5.Pseudo membranous colitis 6.Glossitis 7.Elevated liver enzymes 8.Nausea 9.Vomiting
1.Hpersensitivity to cephalosporins 2.Aong with other nephrotoxic drugs 3.Along with oral anticoagulants 4.Pseudo membranous colitis
Special Precaution: 
1.Renal impairment 2.Patient allergic to penicillins 3.Neuromuscular disorders
Aminoglycosides (Gentamycin, Tobramycin): Nephrotoxicity of aminoglycosides potentiated. Oral anticoagulants: Hypoprothrombinaemic effect potentiated, bleeding complications may occur. Bacteriostatic agents like Chloramphenicol: Decrease efficacy of Cefazolin. Probenecid: Slows tubular excretion and this enhances efficacy. Frusemide & Ethacrynic Acid: Potentiate nephrotoxicity of Cefazolin. Lab. test: Urine Glucose: False positive with Benedicts solution and Fehlings solution. Direct Coomb
Adults: 500mg to 1gm I.M. or I.V. three times daily or four times daily. Maximum adult dose: Up to 12gm/day Children: 25 to 50 mg/kg/day I.M or I.V. three times daily or four times daily. Maximum child dose: 100mg/kg/day

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