CEFUROXIME

Product: 
CEFUROXIME
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Ceftin,Zinnat
Dosages: 
125 MG; 250 mg; 500mg
Unit of Packing: 
Tablets
In treatment of: 
Treatment of uncomplicated UTIS;uncomplicated Gonorrhoea
Adverse Effects: 
.Pain after I.M. injection & thrombophlebitis after I.V. injection. 2.Rashes & allergic manifestations 3.Vaginitis 4.Nephrotoxicity 5.Pseudo membranous colitis 6.Pruritus 7.Candidiasis 8.Glossitis 9.Nausea 10.Vomiting 11.Elevated liver enzymes 12.Neutropenia 13.Thrombocytopenia 14.Hemolytic anemia
Contraiindication: 
1.Hypersensitivity to Cefuroxime or other cephalosporins 2.Along with other nephrotoxic drugs 3.Along with oral anticoagulants 4.Pseudo membranous colitis
Special Precaution: 
1.Pseudomembranous colitis 2.Patients sensitive to Penicillin
Interaction: 
Synergy with aminoglycosides.
Servings: 
Adults: Oral dose: 0.25 to 0.5gm two times daily Parenteral dose: 0.75 to 1.5gm I.M or I.V. thrice daily for 5 to 10 days. Severe infections: 1.5gm I.M. or I.V. four times daily Meningitis: 3gm I.M.or I.V. thrice daily Tonsillitis, Pharyngitis, Urinary tract infections etc.: 125 to 500mg orally twice daily up to 10 days Children:30 to 100mg/kg/day I.M or I.V. three times daily or four times daily Meningitis: Initially 200 to 240mg/kg/day I.V. three times daily or four times daily & continue the therapy with 100mg/kg/day. Tonsillitis, Pharyngitis, Urinary tract infections etc.: Above 1`2 years:same as adult dose Below 12 years: 0.125gm to 0.25gm orally twice daily for 10 days or :20mg/kg/day oral suspension twice daily for 10 days Otitismedia: 30mg/kg/day orally twice daily

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