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CIPROFLOXACIN
Product:
CIPROFLOXACIN
Formulary:
Generic Formulary
Category:
Ear Nose
Sub Group:
AURAL PREPARATIONS
International Brand Name:
Ciloxen,Cipro,Cipro XR,Cipro XL, Ciproxin,Proquin, Cidrax
Dosages:
0.3%W/W
Unit of Packing:
5GM Tube
In treatment of:
Treatment of Otitis Externa
Adverse Effects:
1.Nausea
2.Vomiting
3.Diarrhoea
4.Abdominal discomfort
5.Restlessness
6.Dizziness
7.Drowsiness
8.Arthralgia
9.Rash
10.Confusion
11.Insomnia
12.Anorexia
13.Bad taste
14.Headache
15.Photosensitivity
Contraiindication:
Hypersensitivity to Ciprofloxacin and other Fluoroquinolones
Special Precaution:
1.Hepatic impairment
2.Renal impairment
3.Epilepsy
4.Dehydration
5.Caution while driving the vehicle or operating machine or involved in any hazardous activities.
Interaction:
Antacids (aluminium/magnesium hydroxide), Iron salts, Zinc salts.: Absorption of ciprofloxacin is decreased.
Antineoplastic drugs: Decrease serum levels of ciprofloxacin.
Caffeine: Enhanced efficacy of caffeine.
Oral anti-coagulants: Enhanced efficacy of anti-coagulants.
Cyclosporine: Nephrotoxicity increased by ciprofloxacin.
Theophylline: Increased plasma levels of theophylline resulting in toxicity.
NSAIDs: CNS excitation may occur.
Rifampicin: Decreases serum concenteration of ciprofloxacin.
Chloramphenicol: Antagonises effects of ciprofloxacin.
Servings:
Adults:
Dose is determined on the basis of severity of the infection, type of infecting organism, age, weight and renal function of the patient.
UTI: 0.5 - 1 g / day in 2 divided doses.
Respiratory tract infection, Bone and joint infections, Infectious diarrhoea, ENT infections, .Skin and soft tissue infections, Enteric fever: 1 - 1.5 g / day in 2 divided doses
Typhoid fever, Intra-abdominal infections, Gynaecological infection: 1 g / day in 2 divided doses
Uncomplicated gonorrhea: 250 mg / day
