DOXAPRAM

Product: 
DOXAPRAM
Formulary: 
Generic Formulary
Category: 
Respiratory System
Sub Group: 
RESPIRATORY STIMULANTS
International Brand Name: 
Dopram
Dosages: 
200 MG
Unit of Packing: 
Inj-5ml
In treatment of: 
Post opeartive Respiratory Depression
Adverse Effects: 
1. Headache 2. Dizziness 3. Nausea 4. Vomiting 5. Diarrhoea 6. Seizure 7. Chest pain 8. Heart rate variation 9. Hypertension 10. Laryngospasm 11. Sneezing 12. Urine retention 13. Bronchospasm 14. Hiccups 15. Pruritis 16. Hyperactivity
Contraiindication: 
1. Hypersensitivity to Doxapram 2. Heart failure 3. Hypertension 4. Seizure 5. Head injury 6. Dyspnea 7. Pulmonary embolism 8. Pneumothorax 9. Obstructed air way 10. Acute bronchial asthma 11. Muscle paresis 12. Flail chest 13. Head injury
Special Precaution: 
1. Hepatic impairment 2. Heart diseases 3. Obstructive air way disease
Interaction: 
Sympathomimetics or MAOIs: Additive pressor effects. Halothane, Cyclopropane & Enflurane: Delay initiation of therapy for at least 10 minutes following discontinuation of anaesthetics. Muscle Relaxants: May mask residual effects of muscle relaxants. Theophylline: Agitation, muscle fasciculation and hyperactivity. Morphine: Antagonises morphine induced respiratory depression. Alkaline solutions like Aminophylline, Frusemide & Thiopentone: Precipitation occurs.
Servings: 
Post anaesthesia respiratory stimulation as IV: 0.5 - 1 mg / kg body weight if necessary repeat after 1 hour Drug induced CNS depression: Initial dose IV injection: 2 mg / kg body weight if necessary repeat after 5 minutes and again 1 - 2 hour until patient awakens. Maximum daily dose: 3 g Acute respiratory failure IV infusion: 1.5 - 4 mg / minute

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