DOXEPIN

Product: 
DOXEPIN
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
ANTIPURITICS &SOOTHENING PREPARATION
International Brand Name: 
Aponal, Adapine, Deptran, Sinquan and Sinequan
Dosages: 
5%
Unit of Packing: 
Tube- 15 gm
In treatment of: 
Adverse Effects: 
1. Drowsiness 2. Dizziness 3. Nausea 4. Vomiting 5. Blurred vision 6. Difficulty in micturition 7. Tachycardia 8. Hypotension 9. Arrhythmia 10. Dryness of mouth 11. Constipation 12. Confusion 13. Headache 14. Sedation 15. Urticaria 16. Rash 17. Pruritis 18. Jaundice 19. Anorexia 20. Impotence 21. Loss of libido 22. Galactorrhea 23.Gynecomastia
Contraiindication: 
1.Hypersensitivity to Doxepin 2.Glaucoma 3.Epilepsy 4.Urinary retention.
Special Precaution: 
1.Renal impairment 2.Hepatic impairment 3.Cardiac arrhythmia 4.Myocardial infarction 5.Tachycardia 6.Heart failure 7.Strokes 8.Alcoholics 9.Patient on MAOI therapy (Discontinue the MAO inhibitor at least 2 weeks before Doxepin is started) 10.Slowly withdraw the drug with caution 11.Patient should be cautioned against driving vehicle, operating machine and activities requiring mental alertness and judgment
Interaction: 
Anticholinergics: Enhanced effect of anticholinergics may occur. Barbiturates: Serum level of imipramine decreased; additive respiratory depressant effect. Clonidine: Hypertensive crisis. Dicoumarol: Increase in anticoagulation effects. Disulfiram: Acute organic brain syndrome. Fluoxetine & Haloperidol: Potentiate action of Doxepin. Levodopa: Its bioavailability is reduced, hypertensive episodes. MAOIs, Furazolidone: Seizures, sweating, coma, hyperexcitablilty, hyperthermia, tachycardia, mydriasis, confusion, DIC. (Disseminated Intravascular Coagulation) and death. Oral Contraceptives and Phenothiazines: Increase plasma levels of Doxepin. Smoking: Increases metabolic bio-transformation. Alcohol: Sedative effect of alcohol potentiated.
Servings: 
Adult: 25 mg 3 times daily; dose can be gradually increased until therapeutic response is obtained. Maintenance dose: 100 - 150 mg / day Maximum daily dose: 300 mg Children: Not recommended

Share Us

Kayem Pharma

Generic Medicine for Antimicrobial and Severe Infections, Generic Medicine for Panic Disorder and Agrophobia, Generic Medicine for Tonsillitis, Generic Medicine for Erectile Dysfunction Drugs Cialis, Generic Medicine for Trichomoniasis, Generic Medicine for Amoebiasis, Generic Medicine for Panic Disorder and Agrophobia, Generic Medicine for Anti Depressations and Anxiety, Generic Medicine for Vertigo Migrane, Generic Medicine for Nausea, Generic Medicine for Schizophrenia, Epilepsy and Seizures, Generic Medicine for Parkinsons, Dementia Alzheimers, Generic Medicine for Pancreatic Harmones and Diabetes, Generic Medicine for Rhinitis and Nasal Congestions, Generic Medicine for Amenorrhea Endometriosis, Generic Medicine for Osteoporosis and Brest Cancer, Generic Medicine for Erectile Dysfunction Tadalfil, Generic Antimetic Medicine, Generic Verdenafil Levitra Medicine for E D, Generic Medicine for Herpessimplex, Keratitis and Conjunctivitis, Generic Medicine for Glaucoma and Mydriasis