ERYTHROMYCIN

Product: 
ERYTHROMYCIN
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Ilosone,Ilotycin
Dosages: 
100MG; 125 mg; 250 mg; 500 mg
Unit of Packing: 
Tablets-Chewable
In treatment of: 
Treatment of susceptible infections;Bronhitis;severe Campylobacter Enteritis,Pertussis,chanroid,Diptheria;Pneumonia,Sinisitis;Legionella infections;trnch fever,treatment of susceptible infections in Penicillin-allergic patients;as alternative to Tetracycline for chlamydial
Adverse Effects: 
1.Nausea 2.Vomiting 3.Diarrhea 4.Epigastric pain 5.Fever 6.Rash 7.Urticaria 8.Super infection 9.Dryness 10.Pruritis 11.Cholestatic jaundice 12.Hearing disturbances (Ototoxicity)
Contraiindication: 
1.Hypersensitivity to erythromycin and other macrolide 2.Liver disease
Special Precaution: 
1.Hypersensitivity to erythromycin and other macrolide 2.Liver disease
Interaction: 
Anticoagulants: Efficacy enhanced leading to haemorrhages. Bromocriptine: Efficacy protentiated leading to toxicity. Carbamazepine: Dangerous toxic side effects requiring resuscitative measures and hospitalisation. Digoxin: Serum levels of digoxin enhanced, leading to toxicity. Disopyramide: Increased disopyramide plasma levels leading to arrhythmias. Ergot Alkaloids: Acute ergotism manifested as peripheral ischaemia. Methylprednisolone: Decreases methylprednisolone clearance. Penicillins: Alters efficacy, may be synergistic or antagonist. Theophylline: Increased serum theophylline levels resulting in toxicity. Decreased serum levels of erythromycin. Triozolam: Increased CNS depression.
Servings: 
Adult: 250 - 500 mg every 6 hours Pneumonia: 250 - 500 mg four times daily for 2 - 3 weeks Diphtheria: 500 mg four times daily for 1 - 2 weeks Pertusis: 2 g /day in four divided dose for 2 weeks Chancroid, Urogenital infections: 500 mg every 6 hours for 1 week Urethritis: 500 mg orally four times a day for 7 days Children: 30 - 60 mg/kg body weight/day in 4 divided dose Pnumonia: 50 mg/kg body weight/day in four divided dose for 3 week Conjunctivitis: 50 mg/ kg body weight/day in four divided dose for 2 week

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