International Brand Name:
In treatment of:
Anemia of chronic renal filure,AIDS patient on Zidovudine related Anaemia
1. Exacerbate hypertension
2. Exacerbate seizures
3. Renal impairment
6. Elevated liver enzymes
7. Metalic taste
1. Hypersensitivity to the drug or mammalian cell products or albumin
2. In patients with uncontrolled hypertension
1.Haematocrit should be determined once each week to measure the initial response.
2.Blood pressure must be monitored closely throughout treatment to help titrate the dose.
3.For optimal response to therapy adequate stores of iron are required. The response to therapy is blunted in patients of iron defeciency. If hypertensive encephalopathy occurs, treatement is stopped.
I.V.: Starts with 25 to 50i.u./kg over 1 to 2 minutes; thrice weekly. Increases the dosage in increments of 25i.u./kg at intervals of four weeks based on patient`s response.
Maintenance dosage is individualized; usually Maintenance dosage weekly is; 100 to 300i.u./kg in two to three injections.