ESOMEPRAZOLE

Product: 
ESOMEPRAZOLE
Formulary: 
Generic Formulary
Category: 
Gastrointestinal Tract
Sub Group: 
Hyper Acidity,Reflux,Ulcers
International Brand Name: 
Sompraz, Zoleri, Nexium, Lucen, Esopral; Axagon, Nexiam
Dosages: 
20 MG/ 40 mg
Unit of Packing: 
Tablets
In treatment of: 
Treatment of Gred
Adverse Effects: 
1.Diarrhoea 2.Nausea 3.Abdominal pain 4.Constipation 5.Headache 6.Flatulence 7.Dry mouth
Contraiindication: 
1.Gastric ulcer 2.Gastroesophageal reflux disease 3.Oesophagitis 4.NSAID associated ulceration 5.Duodenal ulcer related to H. pylori infection
Special Precaution: 
1.Hepatic impairment 2.Monitor gastric malignancy
Interaction: 
Esomeprazole may potentially interfere with CYP2Cl9, the major esomeprazole metabolizing enzyme. Esomeprazole may interfere with the absorption of drugs where gastric pH is an important determinant of bioavailability (e.g., ketoconazole, iron salts and digoxin). Esomeprazole does not have any clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin or amoxycillin.
Servings: 
Gastro-oesophageal Reflux Disease (GORD): Healing of erosive oesophagitis: 20mg or 40mg once daily for 4 to 8 weeks. Maintenance of healing of erosive esophagitis: 20mg once daily. Symptomatic gastroesophageal reflux disease: 20mg once daily for 4 weeks. H. pylori eradication to reduce the risk of duodenal ulcer recurrence Esomeprazole: 40mg, once daily for 10 days along with Amoxycillin and Clarithromycin

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