ANTIANGINALS & CORONORY VASOLIDATORS
International Brand Name:
In treatment of:
Management of Angina Pectoris
7. Abdominal pain
12. Postural hypotension
13. Myocardial infarction
14. Elevated liver enzymes
15. Visual impairment
20. Leg cramps
22. Gingival hyperplasia
1. Acute myocardial infarction
2. Hypersensitivity to the drug
3. Unstable angina
4. Heart failure
1. Congestive heart failure
2. Cardiovascular insufficiency
4. Left ventricular outflow obstruction.
5. Hepatic impairment
6. Slowly withdraw the drug with caution
7. Use cautiously in women in reproductive age group
8. Use cautiously along with other antihypertensive drugs
9. The drug may leads to hypotension, tachycardia, and myocardial ischaemia.
Histamine H2 antagonists: May increase bioavailability by 50%.
Digitalis glycosides: Serum digoxin levels may be increased upto 40% approx.
Beta blockers: Concomitant use may result in increase adverse effects due to depressant effect on myocardial contractility.
Phenytoin, Carbamapezine, Barbiturates: Plasma levels of felodipine may be reduced.
Food: Bioavailability not affected by food, however it is increased more than two-fold when taken with doubly concentrated grape fruit juice, compared to water or orange juice.
Starts with 5mg once daily. Increase the dosage up to 10mg once daily at 2 week intervals depending up on the patient`s response.
Maximum dose: 20mg