FURAZOLIDONE

Product: 
FURAZOLIDONE
Formulary: 
Generic Formulary
Category: 
Gastrointestinal Tract
Sub Group: 
ANTI DIARRHOEALS/GI ANTI-INFECTIVES
International Brand Name: 
Depandal M
Dosages: 
100 MG/ 25 mg/ 5 ml
Unit of Packing: 
Tablets
In treatment of: 
Treatment of Giardiasis,Cholera and other GI infections
Adverse Effects: 
1. Dizziness 2. Headache 3. Nausea 4. Vomiting 5. Decreased B.P 6. Deafness with tinnitus 7. Urticaria 8. Fever 9. Arthralgia 10. Disulfiram like reactions with alcohol.
Contraiindication: 
1. Hypersensitivity 2. Along with alcohol
Special Precaution: 
1. Use cautiously in G6PD deficiency 2. Urine colour turns orange which has no clinical significance
Interaction: 
Alcohol: Disulfiram like reaction-facial flushing,light headedness, weakness, lacrimation. Anorexiants: Increased pressor response of anorexiants due to MAO inhibition. Levodopa: Both efficacy and adverse effects of levodopa increased especially hypertensive crisis. Effect lasts for several weeks after stopping furazolidone. Sympathomimetics (indirect & mixed): Increased pressor sensitivity to these agents due to MAO inhibition. TCAs: Hypertension, hyperpyrexia, seizures, tachycardia, acute psychosis. Hypnotics & Sedatives: Dose of hypnotics and sedatives should be reduced. Hypoglycaemics: Potentiates them. Food: Hypertensive crisis with tyramine containing foods.
Servings: 
Adults: 100mg 6 hourly 2 to 7 days depending up on the severity of infections Children: 1.25 mg 6 hourly for 2 to 5 days & up to 10days for Giardiasis

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Kayem Pharma

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