GENTAMICIN

Product: 
GENTAMICIN
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
TOPICAL ANTIBACTERIALS AND ANTIFUNGALS
International Brand Name: 
Gentak
Dosages: 
CREAM
Unit of Packing: 
Tube- 15 gm
In treatment of: 
Bacterial skin infection
Adverse Effects: 
1. Vestibular damage & Ototoxicity 2. Allergic manifestations 3. Nephrotoxicity 4. Dizziness 5. Nausea 6. Vomiting 7. Seizures
Contraiindication: 
1. Hypersensitive to the drug or other amino glycosides 2. Along with chloramphenicol or tetracycline 3. Renal impairment 4. Labyrinthine disorders
Special Precaution: 
1. Renal impairment 2. Neuromuscular disorders
Interaction: 
Amphotericin B, Cisplatin, Cephalosporin, Vancomycin, Methoxyflurane, Frusemide, Bumetanide: Increased nephrotoxicity. Anaesthetics, Neuromuscular blocking agents (Tubocurarine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in Pseudomonas infections. Loop diuretics: Concurrent use of these agents may increase the risk of respiratory paralysis and renal dysfunction. Lab Tests: Aminoglycoside serum levels: Guard against in vitro inactivation of aminoglycosides by b-lactum antibiotics in patients on combination therapy.
Servings: 
Dosage: Adults: 2 to 5mg/kg/day; Thrice daily for a week or more Children: 2 to 2.5mg/kg; Thrice daily.

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