GLIBENCLAMIDE

Product: 
GLIBENCLAMIDE
Formulary: 
Generic Formulary
Category: 
Diabetes
Sub Group: 
ORAL ANTIDIABETICS & RELATED DRUGS
International Brand Name: 
Glyburide,Diabeta, Glynase,micronose, Daonil, Semi-Daonil,Euglucon
Dosages: 
2.5 MG/ 5 mg
Unit of Packing: 
Tablets
In treatment of: 
treatment of type Diabetes Mellitus
Adverse Effects: 
1. Hypoglycemia 2. Nausea 3. Vomiting 4. Diarrhoea 5. Constipation 6. Headache 7. Presthesia 8. Weight gain 9. Hypersensitivity reactions 10. Rashes 11. Photosensitivity 12. Purpura 13. Transient leucopenia 14. Agranulocytosis
Contraiindication: 
1. Hypersensitivity to the drug 2. Diabetic ketoacidosis 3. Diabetic coma 4. Renal impairment
Special Precaution: 
1. Hepatic impairment 2. Malnourished and deliberate individuals 3. Strenous exercise and irregular meals may leads to hypoglycemia
Interaction: 
Hypoglycaemic effect of glibenclamide is enhanced by: Anticoagulants, Androgens, Chloramphenicol, Clofibrate, Fenfluramine, Fluconazole, Gemfibrozil, Histamine H2 antagonists, Magnesium Salts, Methyldopa, MAOIs, Phenylbutazone, Probenecid, Salicylates, Sulfinpyrazone, Sulfonamides, TCAs, & Urinary acidifiers. Hypoglycemic effect of glibenclamide inhibited by the following drugs: Beta-blockers, Cholestyramine, Diazoxide, Hydantoins, Rifampicin, Thiazide diuretics & Urinary alkalisers. Charcoal: Reduces the absorption of glibenclamide thus reducing its efficacy or toxicity. Digitalis glycosides: Co-administration results in increased digitalis serum levels.
Servings: 
Oral: Starts with 2.5mg once daily with breakfast. Adjust the dosage by increments of 2.5mg daily. Maximum dose: 15mg/day Maintenance dosage: 1.25 to 15mg once daily with breakfast or in divided doses; if gastrointestinal disturbances occur.

Share Us

Kayem Pharma

Generic Medicine for Antimicrobial and Severe Infections, Generic Medicine for Panic Disorder and Agrophobia, Generic Medicine for Tonsillitis, Generic Medicine for Erectile Dysfunction Drugs Cialis, Generic Medicine for Trichomoniasis, Generic Medicine for Amoebiasis, Generic Medicine for Panic Disorder and Agrophobia, Generic Medicine for Anti Depressations and Anxiety, Generic Medicine for Vertigo Migrane, Generic Medicine for Nausea, Generic Medicine for Schizophrenia, Epilepsy and Seizures, Generic Medicine for Parkinsons, Dementia Alzheimers, Generic Medicine for Pancreatic Harmones and Diabetes, Generic Medicine for Rhinitis and Nasal Congestions, Generic Medicine for Amenorrhea Endometriosis, Generic Medicine for Osteoporosis and Brest Cancer, Generic Medicine for Erectile Dysfunction Tadalfil, Generic Antimetic Medicine, Generic Verdenafil Levitra Medicine for E D, Generic Medicine for Herpessimplex, Keratitis and Conjunctivitis, Generic Medicine for Glaucoma and Mydriasis