ANTIANGINALS & CORONORY VASOLIDATORS
International Brand Name:
In treatment of:
Longterm management of Stable Angina
7. Orthostatic hypotension
9. Sub lingual burning
1. Hypersensitivity to nitrates
2. Severe hypotension
4. Hypertrophic cardiomyopathy
5. Cerebral haemorrhage
6. Early Myocardial infarction(sub lingual)
8. Along with phosphodiesterase inhibitors.
1. Gradually withdraw the drug with caution, start therapy with lower doses
3. Blood volume depletion
4. Cardio vascular diseases
5. Pulmonary diseases
Alcohol: Severe hypotension and cardiovascular collapse.
Aspirin: Increase serum concentrations of nitrates and their actions.
Antihypertensives, TCAs, Phenothiazine, Calcium channel blockers: Marked symptomatic orthostatic hypotension.
Sidenafil causes dangerous potentiation of hypotension, myocardial infarction and death
Lab Tests: May interfere with the Zlatkis-Zak colour reaction causing a false report of decreased serum cholesterol.
Tablets: 0.5mg at every 3 minutes until therapeutic effect is obtained.
I.V.: 5mcg/minute as infusion. Increase with increments of same dose
Sustained release Formulations: 2.5 to 6.5mg two to three times daily.
Topical: 1.5 to 3cm rubs on three times daily. Use more times if required.