GRISEOFULVIN

Product: 
GRISEOFULVIN
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIFUNGALS
International Brand Name: 
Fulvicin, Grifulvin V, Gris-Peg, Grisactin
Dosages: 
250 MG/500 mg
Unit of Packing: 
Tablets
In treatment of: 
Treatment of Dermatophyte infections
Adverse Effects: 
1.Headache 2.Bleeding 3.Nausea 4.Vomiting 5.Diarrhoea 6.Rash 7.Photosensitivity 8.Granulocytopenia 9.Albuminuria 10.Peripheral neuritis 11.Vertigo
Contraiindication: 
1.Hypersensitivity to Griseofulvin 2.Liver failure 3.Porphyria
Special Precaution: 
Penicillin sensitive patients
Interaction: 
Anticoagulants: Griseofulvin may decrease the efficacy of anticoagulants. Barbiturates: Depress the serum levels of griseofulvin. Oral contraceptives: Efficacy of oral contraceptives decreased leading to breakthrough bleeding, amenorrhoea or pregnancy. Alcohol: Disulfiram like reaction (flushing, nausea, giddiness). Food: High fat meal enhances absorption.
Servings: 
Adult: 125 - 250 mg every 6 hourly Tinea infection of body and skin requires 3 weeks treatment Tinea infection of palm and sole requires 4 - 6 weeks treatment Tinea infection of finger and nail requires 4 - 6 months treatment Tinea infection of toe and nail requires 8 - 12 months treatment

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