Generic Formulary
Sub Group: 
International Brand Name: 
Mitoxana and Ifex
1 gm
Unit of Packing: 
In treatment of: 
Treatment of solid tumours in Cervix,Lungs,Ovary,Testis and Thymus
Adverse Effects: 
1. Nausea 2. Vomiting 3. Lowered resistance to infection 4. Bruising or unusual bleeding 5. Anemia 6. Weakness 7. Sore in mouth 8. Taste changes 9. Diarrhea 10. Loss of appetite 11. Visual changes 12. Black, tarry stools 13. Blood in urine or in stool 14. Cough or hoarseness 15. Fever 16. Chills 17. Somnolence 18. Confusion 19. Coma 20. Seizures 21. Ataxia 22. Hallucination 23. Depressive psychosis 24. Dizziness 25. Disorientation 26. Cranial nerve dysfunction 27. Hemorrhagic cystitis 28. Nephrotoxicity 29. Leucopenia 30. Thrombocytopenia 31. Myelosuppression 32. Liver enzyme elevation 33. Liver dysfunction 34. Alopecia 35. Metabolic acidosis 36. Infection 37. Phlebitis 38. Dermatitis 39. Allergy
1. Hypersensitivity to the drug 2. Bone marrow suppression
Special Precaution: 
1. Bone marrow metastases 2. Granulocytopenia 3. Prior therapy with cytotoxic agents 4. Recent radiation therapy 5. Renal impairment 6. Hepatic impairment 7. Monitor haematological functions periodically
Intravenous- Adult- 1.2g/metre square/day for 5 days, the cycle is repeated for 3 weeks.

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