INDAPAMIDE

Product: 
INDAPAMIDE
Formulary: 
Generic Formulary
Category: 
Cardio Vascular System
Sub Group: 
ANTI HYPERTENSIVE DRUGS
International Brand Name: 
Natrilix
Dosages: 
1.5 MG /2.5 mg
Unit of Packing: 
Tablets
In treatment of: 
Management of Hyper Tension(HTN)
Adverse Effects: 
1. Dizziness 2 Headache 3. Orthostatic hypotension 4. Back pain 5. Infection 6. Rhinitis 7. Pharyngitis 8. Sinusitis 9. Vertigo 10 Nausea
Contraiindication: 
1. Hepatic impairment. 2. Hypersensitivity to the drug 3. Hypersensitivity to Sulfonamides 4. Anuric renal failure 5. Cerebro vascular accidents
Special Precaution: 
1. Renal impairment 2. Progressive Liver diseases 3. Hyper urecaemia and Gout 4. Diabetes mellitus 5. Fluid and electrolyte imbalance 6. Cirrhosis 7. Hyper calcaemia
Interaction: 
Diazoxide: Synergistic action - may cause hyperglycemia, hyperuricaemia and hypotension. Digitalis: Diuretic induced hypokalaemia may precipitate digitalis toxicity. Frusemide: Synergy leading to profound diuresis and greater than predicted electroyte loss. Sulfonylureas: Hypoglycaemic effects enhanced. Chlorpropamide: Hypokalaemia. Propantheline: Bioavailability of indapamide increased. Metoclopramide: Bioavailability of indapamide decreased. NSAID`s: Natriuretic effect of indapamide decreased.
Servings: 
Hyper tension: 1.25mg single daily dose. Increased to 2.5mg if required after 4 weeks. Maximum dose: 5mg/day Edema: 2.5mg single daily dose. Increased to 5mg if required after 1 week.

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