Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
Imdur, Chemydur
10 MG/20 mg/40 mg
Unit of Packing: 
In treatment of: 
Longterm management of Stable Angina & Heart Failure
Adverse Effects: 
1. Headache 2. Weakness 3. Dizziness 4. Methaemoglobinaemia 5. Flushing 6. Palpitation 7. Orthostatic hypotension 8. Sweating 9. Sub lingual burning 10. Rashes
1. Myocardial infarction 2. Hypersensitivity to nitrates 3. Severe hypotension 4. Shock 5. Along with phosphodiesterase inhibitors
Special Precaution: 
1. Gradually withdraw the drug with caution start therapy with lower doses 2. Hypotension 3. Blood volume depletetion 4. Cerebral haemorrhage 5. Glaucoma
Alcohol: Severe hypotension and cardiovascular collapse. Aspirin: Increase serum concentrations of nitrates and their actions. Antihypertensives, TCAs, Phenothiazine, Calcium channel blockers: Marked symptomatic orthostatic hypotension. Lab Tests: May interfere with the Zlatkis-Zak colour reaction causing a false report of decreased serum cholesterol.
10 to 20mg two times daily with 7 hours apart; and first dose in morning. Sustained release forms: 30 to 60mg once daily; Increased to 120mg once daily if required.

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