Generic Formulary
Infections & Infestations
Sub Group: 
International Brand Name: 
0.5GM; 0.75 gm/1 gm
Unit of Packing: 
In treatment of: 
Treatment of Penicillin resistant Gonorrhoea
Adverse Effects: 
1. Ototoxicity mainly cochlear damage and hearing loss 2. Allergic manifestations 3. Nephrotoxicity 4. Dizziness Seizures 5. Nausea Vomiting
1. Hypersensitive to the drug or other amino glycosides 2. Along with other nephrotoxic drugs 3. Renal impairment 4. Auditory disorders
Special Precaution: 
1.Renal impairment 2.Neuromuscular disorders 3.Myasthenia gravis 4.Parkinsonism
Amphotericin B, Cisplatin, Cephalosporin, Vancomycin, Methoxyflurane, Frusemide, Bumetanide: Increased nephrotoxicity. Anaesthetics, Neuromuscular blocking agents (Tubocurarine): Risk of neuromuscular blockade and respiratory paralysis. Penicillin, Cephalosporins, Carbenicillin, Ticarcillin: Exert antibiotic synergism, especially useful in Pseudomonas infections. Loop diuretics: Concurrent use of these agents may increase the risk of respiratory paralysis and renal dysfunction. Lab Tests: Aminoglycoside serum levels: Guard against in vitro inactivation of aminoglycosides by
0.5 to 1 gm intramuscularly twice daily or thrice daily

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