KETOCONAZOLE

Product: 
KETOCONAZOLE
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
TOPICAL ANTIBACTERIALS AND ANTIFUNGALS
International Brand Name: 
Perkhotal, Nizoral
Dosages: 
2 % W/W
Unit of Packing: 
Tube/ Bottles
In treatment of: 
Treatment of Pityriasis Versicolor
Adverse Effects: 
1.Dizziness 2.Headach 3.Nausea 4.Vomiting 5.Diarrhoea 6.Anorexia 7.Gynecomastia 8.Loss of hair 9.Libido 10.Leucopenia 11.Pruritis 12.Psychiatric problems
Contraiindication: 
1.Hypersensitivity to Ketoconazole
Special Precaution: 
Hepatic dysfunction
Interaction: 
Antacids & Histamine H2 antagonists: Increased gastric pH may inhibit ketoconazole absorption. Isoniazid: The bioavailability of Ketoconazole may be decreased. Rifampicin: Decreased serum levels of either drug may occur. Oral anticoagulants: Anticoagulants response may be enhanced. Corticosteroids: Bioavailability of corticosteroids increased and clearance may be decreased, resulting in possible toxicity. Cyclosporine: Efficacy of cyclosporine enhanced leading to nephrotoxicity. May be used beneficially to reduce dose of cyclosporine in some patients. Theophelline: Serum levels of theophylline may be decreased. Alcohol: Nausea and acute facial flushing.
Servings: 
Adult: 200 - 400 mg once daily Prostate carcinoma: 1.2 g in 3 divided dose. TOPICAL PREPARATIONS For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days. Seborrheic dermatitis: apply Ketoconazole twice daily for 1 month Dandruff: Apply for 60 seconds and rinse well. Reapply for 180 seconds. Apply twice weekly for 1 month CHILDREN>2 years: 3.3 - 6.6 mg / kg body weight / day TOPICAL PREPARATIONS For the treatment of Tinea infections apply once or twice daily on the affected part for 14 days. For Tinea pedis, apply for 1

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