KETOROLAC TROMETAMOL

Product: 
KETOROLAC TROMETAMOL
Formulary: 
Generic Formulary
Category: 
Pain & Fever
Sub Group: 
ANALGESICS & ANTIPYRETICS
International Brand Name: 
Toradol and Acular
Dosages: 
10 MG
Unit of Packing: 
Tablets
In treatment of: 
Short term mgt of moderate to severe post opeartive pain
Adverse Effects: 
1. Nausea 2. Drowsiness 3. Dizziness 4. Headache 5. Syncope 6. Transient scalp tingling 7. Orthostatic hypotension 8. Ventricular arrhythmias 9. Nasal stuffiness 10. Broncho spasm 11. Vomiting 12. Diarrhea 13. Muscle spasm 14. Toxic myopathy 15. Dry mouth 16. Ulcer 17. Gastric irritation 18. Oedema 19. Dry mouth
Contraiindication: 
1. Hypersensitivity to this drug 2. Peptic ulcer 3. As a prophylactic analgesic before surgery; pregnancy and lactation 5. In elderly patient there is usually hepatic or renal dysfunction 6. Coagulation disorder
Special Precaution: 
1. Hepatic dysfunction 2. Renal dysfunction and in to be used with caution 3. GI disease 4. Bleeding disorders 5. Patients with hypersensitivity to other Non Steroidal Anti Inflammatory Drugs
Interaction: 
Anticoagulants: May prolong prothrombin time. Beta blockers: Antihypertensive effect may be impaired. Cyclosporine: Nephrotoxicity of both agents may be increased. Lithium: Serum lithium levels may be increased resulting in toxicity. Hydantoins: Serum hydantoins levels resulting in increased efficacy and toxic effects. Methotrexate: Risk of methotrexate toxicity (stomatitis, bone marrow suppression, nephrotoxicity) increased. Aspirin: Plasma concentration of ketorolac may be decreased and may increase the incidence of GI effects.
Servings: 
For Injection- Adults-Initially 60mg i.m. or 30mg i.v. as a single dose, or 30 mg i.m or i.v. every 6 hrs. In the case of renal impaired patient, initially 30mg i.m .or 15mg i.v. as a single doses or multiple doses of 15mg i.m. or i.v.every 6 hrs. For oral- Adults- 20mg as a single dose followed by 10mg every 4 to 6 hrs. In the case of renal impaired patients 10mg as a single dose, followed by 10mg every 4 to 6 hrs.

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