LEFLUNOMIDE

Product: 
LEFLUNOMIDE
Formulary: 
Generic Formulary
Category: 
Musculo Skeletol Disorder
Sub Group: 
NASAIDS(Non Sterodial Anti Inflamatory Drugs)
International Brand Name: 
Arava
Dosages: 
10 MG/20 mg
Unit of Packing: 
Tablets
In treatment of: 
Treatment of active Rheumatoid Arthritis
Adverse Effects: 
1. Diarrhea 2. Hair loss 3. Headache 4. Dizziness 5. Upset stomach 6. Vomiting 7. Stomach pain 8. Loss of appetite 9. Weight loss 10. Mouth sores 11. Runny nose 13. Back pain 14. Dry or itchy skin 15. Muscle pain or weakness 16. Flu-like symptoms 17. Urinary tract infection 18. Rash 19. Difficulty breathing 20. Chest pain 21. Increased heart rate
Contraiindication: 
1. Hypersensitivity to the drug 2. Immunodeficiency 3. Hypopriteinemia
Special Precaution: 
1. Blood problems 2. Disease of the immune system 3. Infections 4. Liver disease 5. Renal disease 6. History of TB
Interaction: 
Cholesturamine, charcoal: Co-administration with lefulnomide results in rapid and significant decrease in lefulnomide activity. Rifampicin: Co-administration increases lefulnomide plasma levels. Hepatotoxic drugs: Co-administration may increase side effects. NSAIDs: Lefulnomide causes an increase in the free fraction of diclofenac and ibuprofen. Tolbutamide: Lefulnomide causes increase in the free fraction of tolbutamide.
Servings: 
Oral- Adult- For rheumatoid arthritis - First, 100 mg once a day for three days, then 20 mg once a day.

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