Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
Prinivil , Tensopril, Zestril
2.5 MG/5 mg/10 mg
Unit of Packing: 
In treatment of: 
Mgt of heart failure
Adverse Effects: 
1. Cough 2. Angioedema 3. Hypotension 4. Chest pain 5. Hyperkalemia 6. Rashes 7. Urticaria 8. Swelling of lips mouth nose and larynx 9. Fetopathic in later half of pregnancy 10. Headache
1. Hypersensitivity to the drug 2. Renal artery stenosis 3. Aortic stenosis 4. Coarctation of aorta
Special Precaution: 
1.Renal impairment: 2.Cardiogenic shock 3.Severe heart failure 4.Anaesthesia 5.Surgery 6.Stops diuretics 2 to 3 days before therapy
Antacids : Decrease efficacy of Lisinopril. Indomethacin : Reduces hypotensive effect. Digoxin : Increases plasma digoxin levels. Potassium preparations & Postassium sparing diuretics : Hyperkalaemia and increased risk of renal failure. Lithium : Toxicity due to increased serum concentration of Lithium. Immunosuppressive Drugs : Increased risk of bone marrow depression. Antidepressants , Diuretics, Beta-Blockers, Phenothiazines : Enhance hypotensive effect. Morphine : Enhanced analgesic effect and respiratory depression.
Starts with 2.5mg once daily. Increases the dose to 5 to 20mg once daily; depending on patient`s response if required. Maximum dose: 40mg/day

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