Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
Mevacor ,Rovacor
10 MG/20 mg
Unit of Packing: 
In treatment of: 
Treatment of Hypercholesterolaemia (Type IIA & II B). Hyper Lipoproteinaemias
Adverse Effects: 
1. Headache 2. Dizziness 3. Vertigo 4. Tremor 5. Peripheral neuropathy 6. Myalgia 7. Arthralgia 8. Myositis 9. Muscle cramps 10. Rhabdomyolysis 11. Memory loss 12. Taste impairment 13. Anxiety 14. Depression 15. Insomnia 16. Abdominal discomfort 17. Heart burn 18. Abdominal pain 19. Nausea 20. Blurred vision 21. Abnormal liver function tests 22. Rash 23. Pruritus 24. Alopecia 25. Photosensitivity 26. Cholestatic jaundice 27. Pancreatitis
1. Hypersensitivity to the drug 2. Active liver diseases 3. Persistent elevation of serum transaminase levels
Special Precaution: 
1. Renal impairment 2. History of liver diseases 3. Alcoholics
Cyclosporine, erythromycin, niacin, gemfibrozil: Severe myopathy or rhabdomyolysis. Propranolol: Decrease in antihyperlipidaemic activity. Itraconazole: Plasma levels of lovastatin increased 20-fold. Warfarin: Anticoagulant effect increased, chances of bleeding.
Starts with 10 to 20mg once daily; with evening meals. Increased if required. Maximum dose: 80mg In severely elevated cholesterol levels starts with 40mg.

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