MEFLOQUINE

Product: 
MEFLOQUINE
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIMALARIALS
International Brand Name: 
Mefaquin,Lariam
Dosages: 
250 MG
Unit of Packing: 
Tablets
In treatment of: 
Treatment of Malaria: CONTROLLED SUBSTANCE
Adverse Effects: 
1.Nausea 2.Vomiting 3.Diarrhoea 4.Abdominal cramps 5.Bitter taste 5.Ataxia 6.Dizziness 7.Hallucination 8.Pruritis
Contraiindication: 
1.Hypersensitivity to Mefloquine 2.Epilepsy 3.Anxiety disorder 4.Psychosis
Special Precaution: 
1.Hepatic dysfunction 2.Renal impairment 3.Heart failure 4.Do not drive or operate machines during or up to 3 week 5.Epilepsy 6.Psychiatric problems
Interaction: 
Beta adrenergic blockers: Cardiac arrest may occur with concurrent mefloquine. Chloroquine: Risk of convulsion may be increased. Quinine or Quinidine: Do not use concurrently with mefloquine. Valproic acid: Loss of seizure control and lower than expected valproic acid blood levels.
Servings: 
Adult: Treatment of Malaria: 25 mg base / kg body weight in single or divided dose; Maximum dose: 1.5 g Prophylaxis: 250 mg of salt /week taken 2 week before entering an endemic area and 4 weeks after leaving. Children: 10 - 25 mg / kg body weight / week in single dose

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