International Brand Name:
Urometaxan , MESNEX , Uromitexan
In treatment of:
Treatment of acute Lymphoblastic Leukaemia and Myeloid Lukaemias
1. Bad taste in mouth
3. Soft stool
8. Blood in urine
9. Skin rash
14. Limp pain
Contraindicated in patients with hypersensitivity to mesna and to other thiol containing compounds
1. With ketone urea
2. Engaging in activities which require alertness such as driving or using machinery
Adults-Mesna dose depend upon the amount of ifosfamide and cyclophosphamide that a patient receives. The standard dose depends equal to 20% of the total ifosfamide given at three separate time interval through a vein infused over at least 5 minute, first dose is right before the ifosfamide, often referred to as 0 hr, the 2nd dose is 4 hr after the start of the infusion and the 3rd dose is 8 hrs after the start of infusion.
Mesna can also be administered through orally by mixing with flavoured drink like grape juice, cola, chocolate and milk etc.