METHOXSALEN

Product: 
METHOXSALEN
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
PSORIASIS,SEBORRHOEA,ICHTHYOSIS
International Brand Name: 
Methoxsalen
Dosages: 
10 MG' 1% W/V
Unit of Packing: 
Tablets/ Bottles
In treatment of: 
Treatment of Psoriasis
Adverse Effects: 
1.Nausea 2.Abdominal discomfort 3.Diarrhoea 4.Headache 5.Dizziness 6.Nervousness 7.Peeling 8.Itching 9.Blistering 10.Erythema 11.Photosensitivity reactions 12.Insomnia 13.Leg cramps 14.Burns
Contraiindication: 
1.Hypersensitivity to Methoxsalen. 2.Photosensitivity includes lupus erythematosus,Porphyria cutanea tarda,erythropoietic proto porphyria,Xeroderma pigmentosum. 3.Aphakia. 4.Invasive squamous cell carcinoma. 5.Albinism. 6.History of melanoma 7.Jaundice
Special Precaution: 
1.Hepatic impairment 2.History of sunlight allergy 3.Gastrointestinal diseases 4.Avoid contact with eye lids, lips, genitals 5.Avoid exposure to sunlight, artificial UV emission
Interaction: 
Ultraviolet light & overexposure to sunlight: May result in severe burns. Drugs known to cause photosensitation - Griseofulvin, phenothiazines, nalidixic acid, halogenated salicylanilides, tetracyclines, thiazides: Special care should be excercised in treating patients who are taking these drugs.
Servings: 
Oral: Psoriasis, Vitiligo: 600 mcg/kg to be taken 2-4 hours before exposure to UV light for 2 times a week (minimum 2 days interval between the doses) Topical: 1% Methoxsalen and its diluted solutions are used.

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