NALOXONE

Product: 
NALOXONE
Formulary: 
Generic Formulary
Category: 
Poisonning and Drug Dependance
Sub Group: 
ALCOHOLISM
International Brand Name: 
naloxone
Dosages: 
200 MCG/ML; 400mcg/ml
Unit of Packing: 
Amp- 2ml
In treatment of: 
Treatment of Opioid -induced depression in neonates due to obstetric analgesia
Adverse Effects: 
1.Nausea 2.Vomiting 3.Hypotension 4.Hypertension 5.Cardiac arrhythmias 6.Pulmonary oedema 7.Seizures 8.Ventricular fibrillation
Contraiindication: 
1.Hypersensitivity to Naloxone 2.Patient on Opioid therapy 3.Acute opioid withdrawal 4.Liver failure
Special Precaution: 
1.Hepatic impairment 2.Renal impairment 3.Opioid dependence 4.Cardiac disease
Interaction: 
Servings: 
Postoperative Opiate Depression: 0.1-0.2 mg IV in adults or 0.005-0.01 mg IV in children, given at 2- to 3-minute intervals until the desired response is obtained. Dose can be repeated IV or IM after 1 - 2 hour intervals depending on the response of the patient and the dosage and duration of action of the opiate administered. Neonatal Opiate Depression: 0.01 mg/kg, administered into the umbilical vein of the neonate at 2- to 3-minute intervals until the desired response is obtained. If required doses may be repeated at 1- 2 hour intervals depending on the response of the neonate and the dosage and duration of action of the opiate administered to the mother. When the IV route cannot be used, the drug may be administered by IM or subcutaneous injection. Opioid poisoning: Adult: 0.4-2 mg IV, administered at 2- to 3-minute intervals if necessary. Children: 0.01 mg/kg; if this dose does not produce the desired degree of response, a subsequent dose of 0.1 mg/kg may be administered. Opiate addiction (oral): 200 mg to 3 g daily.

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Kayem Pharma

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