NETILMICIN

Product: 
NETILMICIN
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Dosages: 
50 MG/ 300 mg
Unit of Packing: 
Inj- 1 ml
In treatment of: 
Treatment of infections caused by susceptible Bacteria
Adverse Effects: 
1.Vestibular damage 2.Ototoxicity 3.Hearing loss 4.Nausea 5.Vomiting 6.Allergic manifestations 7.Nephrotoxicity
Contraiindication: 
1. Hypersensitive to the drug or other amino glycosides 2. Renal impairment 3. Labyrinthine disorders
Special Precaution: 
1.Renal impairment: 2.Neuromuscular disorders 3.Dehydration
Interaction: 
Aminoglycosides, vancomycin, methoxyflurane, enflurane, cephaloridine: Increased nephrotoxicity. Loop diuretics: The auditory toxicity appears to be increased. Polypeptide antibiotics: Concurrent use of these agents may increase risk of respiratory paralysis and renal dysfunction. Anaesthetics, neuromuscular blocking agents (Tubocurarine, Gallamine): Risk of neuromuscular blockade and respiratory paralysis. Pencillin, cephalosporins, carbenicillin, ticarcillin: Exert antibiotic synergism, especially useful in psuedomonas infections. Lab tests: Aminoglycoside serum level: Guard against in vitro inactivation of aminoglycosides by beta-lactum antibiotics in patients on combination therapy.
Servings: 
Adults: 4 to 6 mg/kg/day in 1 to 3 divided doses. In severe infections dose may be increased up to 7.5mg/kg/day in 3 divided doses. Children: 5.5 to 8 mg/kg/day in 2 - 3 divided doses. Neonates: 4 to 6.5 mg/kg/day in 2 divided doses. Urinary tract infections: 1.5 to 2mg/day in 2 divided doses.

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