PARACETAMOL

Product: 
PARACETAMOL
Formulary: 
Generic Formulary
Category: 
Pain & Fever
Sub Group: 
ANALGESICS & ANTIPYRETICS
International Brand Name: 
Acetaminophen
Dosages: 
500MG/650 mg/120 mg/5ml; 250mg/5 ml
Unit of Packing: 
Tablets
In treatment of: 
Analgesic. Releif of mild to moderate pain & fever
Adverse Effects: 
1. Nausea 2. Abdominal distress 3. Allergic reactions 4. Rash
Contraiindication: 
1. Hypersensitivity to Paracetamol
Special Precaution: 
1. Hepatic impairment 2. Renal impairment 3. Hypertension
Interaction: 
Cholestyramine: Reduces absorption of paracetamol. Charcoal: Activated, administered immediately reduces absorption of paracetamol. Domperidone and metochlopramide: Enhance absorption of paracetamol. Alcohol: Chronic excessive ingestion of alcohol potentiates hepatotoxicity of paracetamol. Zidovudine: Effects zidovudine may be decreased.
Servings: 
Adult: 500 - 1000 mg in 3 times daily Maximum dose: 4 g / day For migraine: 500 mg to be taken at the first sign of migraine attack and repeated 4 - 6 hourly until suppress mild attacks. Children: 60 mg / kg body weight /day in 4 divided doses.

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