PEFLOXACIN

Product: 
PEFLOXACIN
Formulary: 
Generic Formulary
Category: 
Infections & Infestations
Sub Group: 
ANTIBACTERIALS
International Brand Name: 
Dosages: 
200MG/ 400 mg
Unit of Packing: 
Tablets
In treatment of: 
Treatment of susceptible infections
Adverse Effects: 
1.Nausea 2.Vomiting 3.Diarrhoea 4.Abdominal discomfort 5.Restlessness 6.Dizziness 7.Drowsiness 8.Arthralgia 9.Rash 10.Confusion 11.Insomnia 12.Anorexia 13.Bad taste 14.Headache 15.Photosensitivity
Contraiindication: 
Hypersensitivity to Pefloxacin and other Fluoroquinolones
Special Precaution: 
1.Hepatic impairment 2.Renal impairment 3.Caution while driving the vehicle or operating machine or involved in any hazardous activities
Interaction: 
Antineoplastic drugs: Decrease serum levels of pefloxacin. Caffeine: Enhanced efficacy of caffeine. Oral anti-coagulants: Enhanced efficacy of anti-coagulants. Cyclosporine: Nephrotoxicity increased by pefloxacin. Theophylline: Increased plasma levels of theophylline resulting in toxicity. NSAIDs: CNS excitation may occur. Rifampicin: Decreases serum concentration of pefloxacin. Chloramphenicol: Antagonises effects of pefloxacin.
Servings: 
Adults: 800 mg / day in 2 divided doses Gonorrhoea: 800 mg / day in single dose

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