International Brand Name:
In treatment of:
Management of Hyper Tension(HTN)
7.Swelling of lips, mouth, nose, and larynx
8.Fetopathic in later half of pregnancy
18.Decreased haemoglobin count
20.Elevated liver enzymes
21.Acute renal failure is precipitated in renal artery stenosis
1.Hypersensitivity to the drug
2.Renal artery stenosis
4.Coarctation of aorta
3.Ischaemic heart disease
4.Severe heart failure
5.Collagen vascular diseases
8.Lower dosage is needed for elderly
Nitrates, Diuretics, Beta-blockers, Anti-depressants, Alcohol, Calcium channel blockers: Enhanced hypotensive effect.
Potassium sparing diuretics: Hyperkalaemia.
Sex hormones: Oestrogens and combined oral contraceptives antagonise hypotensive effect.
Starts with 4mg; orally once daily. Increases the dose to 8mg once daily or in two divided doses; after one month of therapy depending on patient`s response.
Maximum dose: 16mg/day
In CHF patients starts the dosage with 2mg once daily dosage and gradually increases at 1 to2 weeks` intervals to 4mg or further increase in dose depends up on patient`s response.