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PHYTOMENADIONE
Product:
PHYTOMENADIONE
Formulary:
Generic Formulary
Category:
Nutrition & Metabolism
Sub Group:
VITAMINS
International Brand Name:
Dosages:
1MG
Unit of Packing:
Vial
In treatment of:
Vitamin K defeciency due to Drugs malabsorption over anticoagulation
Adverse Effects:
1. Nausea
2. Vomiting
3. Headache
4. Dizziness
5. Convulsive movements
6. Hypotension
7. Arrhythmias
8. Rapid and weak pulse
9. Diaphoresis
10. Flushing
11. Erythema
12. Urticaria
13. Pruritus
14. Rash
15. Bronchospasm
16. Dyspnea
17. Anaphylactic reactions
18. Kernicterus
Contraiindication:
1. Hypersensitivity to the drug
Special Precaution:
Not Available
Interaction:
Anticoagulants: It may be necessary to increase the anticoagulant dose.
Mineral oil: May decrease Gl absorption of vitamin K.
Servings:
Hypoprothrombinemia due to Vitamin K malabsorption or drug therapy or inadequate bile secretion: 5 to 10mg/day orally. Adjust the dosage based on patient`s response.
Hypoprothrombinemia due to Vitamin K malabsorption or drug therapy or excess vitamin A: 2 to 25mg orally or parenterally. Increases the dosage up to 50mg if required.
Children: 5 to 10mg
Infants: 2mg
Hypoprothrombinemia due to oral anticoagulants:2.5 to 10mg orally, subcutaneously or intramuscularly. Repeated if required.
For emergency management: 10 to 50mg as slow I.V; rate not more than 1mg/minute. Repeated four times daily or three times daily if required.
Hypoprothrombinemia due to vitamin K deficiency due to long term parenteral nutrition: 5 to 10mg; intramuscularly weekly.
Children: 2 to 5mg
Hemorrhagic disease in neonates: 500mcg to 1000mcg S.C. or I.M. immediately after birth. Repeated in two to three weeks if needed.
