POLYMYXIN B

Product: 
POLYMYXIN B
Formulary: 
Generic Formulary
Category: 
Skin
Sub Group: 
TOPICAL ANTIBACTERIALS AND ANTIFUNGALS
International Brand Name: 
Polybactrin , Gregoderm
Dosages: 
5000 IU+3400IU+400 IU/G
Unit of Packing: 
Tube - 5 gm
In treatment of: 
Treatment of Skin infections
Adverse Effects: 
1.Pain at the site of injection 2.Nystagmus 3.Flushing 4.Nausea 5.vomiting 6.Diarrhoea 7.Rash 8.Partial deafness 9. Pruritis 10.Ataxia 11.Vertigo 12.Nephrotoxicity 13.Disturbances of vision
Contraiindication: 
1. Hypersensitive to Polymixin B and other polypeptide antibiotic
Special Precaution: 
1.Myasthenia gravis 2.Renal dysfunction
Interaction: 
Aminoglycosides: Concurrent use may increase risk of respiratory paralysis and renal dysfunction. Non-depolarising muscle relaxants: Neuromuscular blockade may be enhanced.
Servings: 
Adult :( IV) DOSE: 15000 - 25000 units /kg body weight/day in divided dose for 1 - 2 week Children (IV) dose: 20000 - 40000 units/kg body weight/day in divided dose.

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