Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
Pravachol , Selektine
10 MG/20 mg
Unit of Packing: 
In treatment of: 
Treatment of Hypercholesterolaemia (Type IIA & II B). Hyper Lipoproteinaemias
Adverse Effects: 
1.Headache 2.Abdominal discomfort 3.Heart burn 4.Abdominal pain 5.Nausea 6.Dyspepsia 7.Flatulence 8.Constipation 9.Abnormal liver function tests 10.Abnormal thyroid function tests 11.Urinary abnormality 12.Rash 13.Pruritus 14.Photosensitivity 15.Fatigue 16.Myositis 17.Chest pain 18.Myopathy 19.Rhabdomyolysis 20.Upper respiratory tract infections
1.Hypersensitivity to the drug 2.Active liver diseases 3.Persistent elevation of serum transaminase levels
Special Precaution: 
1.Monitor hepatic and liver function tests and lipid levels before and periodically during therapy and stop drug if there is marked elevation of creatinine phosphokinase level 2.History of liver diseases 3.Renal impairment 4.Alcoholics
Bile Acid Sequestrants (BAS): When pravastatin is administered 1hour before or 4 hours after BAS, there is no clinically significant decrease in bioavailability or therapeutic effect. Gemfibrozil : Combination therapy generally not recommended.
Oral: Starts with 10mg to 20mg once daily; at bed time. Increased if required based on patients response. Maximum dose: 40mg

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