Generic Formulary
Cardio Vascular System
Sub Group: 
International Brand Name: 
1 MG/2 mg
Unit of Packing: 
In treatment of: 
Management of Hyper Tension(HTN)
Adverse Effects: 
1.Postural hypotension 2.Headache 3.Drowsiness 4.Dizziness 5.Dryness of mouth 6.Nasal congestion 7.Rash 8.Blurred vision 9.Palpitation 10.Weakness 11.Impairment of ejaculation in males 12.Fluid retention
1.Hypersensitivity to the drug 2.CHF due to mechanical obstruction
Special Precaution: 
1.Angina pectoris 2.Renal impairment 3.Hepatic impairment 4.Phaeochromocytoma 5.To avoid withdrawal syndrome gradually withdraw with caution 6.Use with caution along with other anti hypertensive drugs 7.Started with low dose usually given at bed time
Clonidine: Antihypertensive effect of clonidine may be decreased. Beta-adrenergic blocking agents: May enchance "first dose" acute postural hypotension of prazosin. Indomethacin: Antihypertensive effect of prazosin decreased. Verapamil & Nifedipine: Acute hypotensive effect when coadministered with prazosin. Lab tests: False positive results may occur in screening tests for phaeochromocytoma in patients receiving prazosin.
Hypertension: Starts with 500mcg at bed time, Then 500mcg 12th hourly or 8th hourly in first week & 1mg 12th hourly or 8th hourly in second week. Dose gradually increases up to 20mg/day in divided doses if required. Benign prostatic hypertrophy: Starts with 500mcg at bed time. Then 500mcg 12th hourly in first week. Dose gradually increases up to 1 to 3 mg 12th hourly

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